Receptor signaling: When dimerization is not enough

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Receptor signaling: When dimerization is not enough

Activation of receptors that signal via tyrosine kinase domains has been thought to involve receptor dimerization and transphosphorylation of juxtaposed catalytic domains. Recent results suggest things might be more complex - specific intersubunit conformational changes within a dimer can also be important.

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ژورنال

عنوان ژورنال: Current Biology

سال: 1999

ISSN: 0960-9822

DOI: 10.1016/s0960-9822(99)80357-1